Professional Profile

After working in the biotech industry for 10 years as a Principal Scientist and a Program Manager, I joined KTRDC in 2003 and currently serve as the Executive Director and a Professor in the Department of Plant and Soil Sciences.

Research Interests

• Transcriptional regulation of plant secondary metabolic pathways and the mechanistic roles of functional domains of transcription factors;
• Application of advanced technologies, such as genome editing, for crop design.
• Protein engineering to modify genes and protein functions

Teaching 

• Fall/Spring semesters: ABT 301. Writing and Presentation in Life Sciences
• Spring semesters: PLS609. Plant Biochemistry

Additional Information

Publications

Lim ARQ, Kong Q, Noor A, Song YQ, Pattanaik S, Yuan L, Ma W (2023) B-BOX-DOMAIN PROTEIN32 modulates seed oil biosynthesis in Arabidopsis by interacting with WRINKLED1. Plant Physiology 193:2919–922.

Jie Zhang, Liheng He, Jingjing Dong, Cailiang Zhao, Yujie Wang, Ruimin Tang, Wenbin Wang, Zhixian Ji, Qinghe Cao, Hong’e Xie, Zongxin Wu, Runzhi Li, Ling Yuan, Xiaoyun Jia (2023) Integrated metabolic and transcriptional analysis reveals the role of carotenoid cleavage dioxygenase 4 (IbCCD4) in carotenoid accumulation in sweetpotato tuberous roots. Biotechnology for Biofuels and Bioproducts. 16(1): 45 

Wenwen Liu, Huayuan Mu, Ling Yuan, Yang Li, Yuting Li, Shenchang Li, Chong Ren, Wei Duan, Peige Fan, Zhanwu Dai, Yongfeng Zhou, Zhenchang Liang, Shaohua Li, Lijun Wang (2023) VvBBX44 and VvMYBA1 form a regulatory feedback loop to balance anthocyanin biosynthesis in grape. Horticulture Research. 10(10):uhad176

Hou X, Singh SK, Werkman JR, Liu Y, Yuan Q, Wu X, Patra B, Sui X, Lyu R, Wang B, Liu X, Li Y, Ma W, Pattanaik S, Yuan L (2023) Partial desensitization of MYC2 transcription factor alters the interaction with jasmonate signaling components and affects specialized metabolism. International Journal of Biological Macromolecules. 252:126472

Liu Y, Singh SK, Pattanaik S, Wang H, Yuan L (2023) Light regulation of the biosynthesis of phenolics, terpenoids, and alkaloids in plants. Communications Biology. 6(1):1055.

Chen H, Liu X, Li S, Yuan L, Mu H, Wang Y, Li Y, Duan W, Fan P, Liang Z, Wang L (2023) The class B Heat Shock Factor HSFB1 regulates heat tolerance in grapevine. Horticulture Research; uhad001, https://doi.org/10.1093/hr/uhad001

Yin Q, Wu T, Gao R, Wu L, Shi Y, Wang X, Wang M, Xu Z, Zhao Y, Su X, Su Y, Han X, Yuan L, Xiang L, Chen S (2023) Multi-omics reveal key enzymes involved in the formation of phenylpropanoid glucosides in Artemisia annua. Plant Physiology and Biochemistry. 201:107795.

Zeng J, Huang Y, Zhou L, Liang X, Yang C, Wang H, Yuan L, Wang Y, Li Y. (2023) Histone deacetylase GiSRT2 negatively regulates flavonoid biosynthesis in Glycyrrhiza inflata. Cells. 12(11):1501.

Fan W, Wang Y, Zhang L, Fang Y, Yan M, Yuan L, Yang J, Wang H. (2023) Sweet potato ADP-glucose pyrophosphorylase small subunit affects vegetative growth, starch content and storage root yield. Plant Physiology and Biochemistry. doi: 10.1016/j.plaphy.2023.107796

Yang Y, Kong Q, Tee WT, Li Y, Low PM, Patra B, Guo L, Yuan L, Ma W. (2023) Transcription factor bZIP52 modulates Arabidopsis seed oil biosynthesis through interaction with WRINKLED1. Plant Physiology. doi: 10.1093/plphys/kiad270

Ren G, Li L, Patra B, Li N, Zhou Y, Zhong C, Wang Y, Yuan L, Wang X. (2023) GhTCP7 suppresses petal expansion by interacting with the WIP-type zinc finger protein GhWIP2 in Gerbera hybrida. Journal of Experimental Botany. doi: 10.1093/jxb/erad152

Ali MF, Shin J-M, Fatema U, Kurihara D, Berger F, Yuan L, Kawashima T (2023) Cellular dynamics of coenocytic endosperm development in Arabidopsis thaliana. Nature Plants 9: 330-342.

Yang C, Shi G, Li Y, Luo M, Wang H, Wang J, Yuan L, Wang Y, Li Y (2023) Genome-wide identification of SnRK1 catalytic alpha subunit and FLZ proteins in Glycyrhizza inflata Bat. highlights their potential roles in licorice growth and abiotic stress responses. International Journal of Molecular Science 24, 121. https://doi.org/10.3390/ijms24010121

Mu H, Li Y, Yuan L, Jiang J, Wei Y, Duan W, Fan P, Li S, Liang Z, Wang L. (2023) MYB30 and MYB14 form a repressor-activator module with WRKY8 that controls stilbene biosynthesis in grapevine. Plant Cell 35: 552-573.

Shin JM, Yuan L, Kawashima T. (2022) Live-cell imaging reveals the cellular dynamics in seed development. Plant Science. 325:111485.

Wu Z, Singh SK, Lyu R, Pattanaik S, Wang Y, Li Y, Yuan L, Liu Y. (2022) Metabolic engineering to enhance the accumulation of bioactive flavonoids licochalcone A and echinatin in Glycyrrhiza inflata (licorice) hairy roots. Frontiers in Plant Science. 13:932594.

Singh SK, Patra B, Singleton JJ, Liu Y, Paul P, Sui X, Suttipanta N, Pattanaik S, Yuan L (2022) Identification and Characterization of Transcription Factors Regulating Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus. Methods in Molecular Biology. 2505:203-221.

Liao B, Shen X, Xiang L, Guo S, Chen S, Meng Y, Liang Y, Ding D, Bai J, Zhang D, Czechowski T, Li Y, Yao H, Ma T, Howard C, Sun C, Liu H, Liu J, Pei J, Gao J, Wang J, Qiu X, Huang Z, Li H, Yuan L, Wei J, Graham I, Xu J, Zhang B, Chen S. (2022) Allele-aware chromosome-level genome assembly of Artemisia annua reveals the correlation between ADS expansion and artemisinin yield. Molecular Plant. S1674-2052(22)00180-0

Yang Y, Kong Q, Lim ARQ, Lu S, Zhao H, Guo L, Yuan L, Ma W. (2022) Transcriptional regulation of oil biosynthesis in seed plants: Current understanding, applications, and perspectives. Plant Communication. Apr 20;100328.

Patra B, Liu Y, Singleton JJ, Singh SK, Pattanaik S, Yuan L. (2022) Virus-induced gene silencing as a tool to study regulation of alkaloid biosynthesis in medicinal plants. Methods in Molecular Biology. 2469:155-164.

Ma T, Gao H, Zhang D, Sun W, Yin Q, Wu L, Zhang T, Xu Z, Wei J, Su Y, Shi Y, Ding D, Yuan L, Dong G, Leng L, Xiang L, Chen S. (2022) Genome-wide analysis of light-regulated alternative splicing in Artemisia annua L. Frontiers in Plant Science. 12:733505

Kong Q, Low PM, Lim ARQ, Yang Y, Yuan L, Ma W. (2022) Functional antagonism of WRI1 and TCP20 modulates GH3.3 expression to maintain auxin homeostasis in roots. Plants (Basel) 11(3):454.

Lim ARQ, Kong Q, Singh SK*, Guo L, Yuan L, Ma W (2022) Sunflower WRINKLED1 plays a key role in transcriptional regulation of oil biosynthesis. International Journal of Molecular Sciences. 23(6):3054

Liu YL, Patra B, Singh SK, Paul P, Zhou Y Li YQ, Wang Y, Pattanaik S, Yuan L. (2021) Terpenoid indole alkaloid biosynthesis in Catharanthus roseus: effects and prospects of environmental factors in metabolic engineering. Biotechnology Letters. (in press)

He S, Wang H, Hao Xi, Wu Y, Bian X, Yin M, Zhang Y, Fan W, Dai H, Yuan L, Zhang P, Chen L. (2021) Dynamic network biomarker analysis discovers IbNAC083 in initiation and regulation of sweet potato root tuberization. The Plant Journal. 108:793-813.

Lyu R, Ahmed S, Fan W, Yang J, Wu X, Zhou W, Zhang P, Yuan L, Wang H. (2021) Engineering properties of sweet potato starch for industrial applications by biotechnological techniques including genome editing. International Journal of Molecular Sciences. 22(17):9533.

Ma T, Gao H, Zhang D, Sun W, Yin Q, Wu L, Zhang T, Xu Z, Wei JH, Su Y, Shi Y, Ding D, Yuan L, Dong G, Leng L, Xiang L, Chen S. (2021) Genome-wide analysis of light-regulated alternative splicing in Artemisia annua L. Frontiers in Plant Science. 12:733505.

Lyu R, Singh SK, Liu Y, Patra B, Zhou Y, Wang B, Pattanaik S, Yuan L. (2021) Reprogramming plant specialized metabolism by manipulating protein kinases. aBiotech. 1-14.

Huang R, Liu M, Gong G, Wu P, Patra B, Yuan L, Qin H, Wang X, Wang G, Liao H, Gao L, Yang C, Li H, Zhang S. (2021) The Pumilio RNA-binding protein APUM24 regulates seed maturation by fine-tuning the BPM-WRI1 module in Arabidopsis. Journal of Integrated Plant Biology. 63(7): 1240-1259.

Zhong C, Patra B, Tang Y, Li X, Yuan L, Wang X. (2021) A transcriptional hub integrating gibberellin-brassinosteroid signals to promote seed germination in Arabidopsis. Journal of Experimental Botany. 72(13):4708-4720.

Li Y, Liang X, Zhou X, An Y, Li M, Yuan L, Li Y, Wang Y (2021) Spatio-temporal selection of reference genes in the two congeneric species of Glycyrrhiza. Scientific Reports. 11(1):1122.

Singh SK, Patra B, Paul P, Pattanaik S, Yuan L. (2021) BHLH IRIDOID SYNTHESIS 3 is a member of a bHLH gene cluster regulating terpenoid indole alkaloid biosynthesis in Catharanthus roseus. Plant Direct. 2021l 00:e00305. 

Li Z, Li X, Zhang Q, Yuan L, Zhou X. (2020) Reference gene selection for transcriptional profiling in Cryptocercus punctulatus, an evolutionary link between Isoptera and Blattodea. Scientific Reports. 10(1):22169.

Liu X, Singh SK, Patra B, Liu Y, Wang B, Wang J, Pattanaik S, Yuan L. (2020) Protein-phosphatase NtPP2C2b and MAP-kinase NtMPK4 act in concert to modulate nicotine biosynthesis. Journal of Experimental Botany. 72(5):1661-1676.

Li Y, Liang X, Zhou X, Wu Z, Yuan L, Wang Y, Li Y. (2020) Selection of Reference Genes for qRT-PCR Analysis in Medicinal Plant Glycyrrhiza under Abiotic Stresses and Hormonal Treatments. Plant (Basel) 9(11):E1441.

Singh SK, Richmond MD, Pearce RC, Bailey WA, Hou X, Pattanaik S, Yuan L. (2020) Maleic hydrazide elicits global transcriptomic changes in chemically topped tobacco to influence shoot bud development. Planta. 252(4):64.

Shoji, T and Yuan, L (2020) ERF clusters: working together to regulate metabolism. Trends in Plant Science. S1360-1385(20)30245-4.

Kong Q, Yang Y, Low PM, Guo L, Yuan L, Ma W (2020) The function of the WRI1-TCP4 regulatory module in lipid biosynthesis. Plant Signal and Behavior. 15(11):1812878.

Yuan, L and Grotewold, E (2020) Plant specialized metabolism. Plant Science.  298:110579.

Kong Q, Singh SK, Mantyla JJ, Pattanaik S, Guo L, Yuan L, Benning C, Ma W (2020) TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR 4 interacts with WRINKLED1 to mediate seed oil biosynthesis. Plant Physiology. 184(2):658-665.

Shin JM, Yuan L, Ohme-Takagi M, Kawashima T. (2020) Cellular dynamics of double fertilization and early embryogenesis in flowering plants. Journal of Experimental Zoology Part B Molecular and Developmental Evolution. 2020:1-10. doi: 10.1002/jez.b.22981.

Yuan, L. (2020) Clustered ERF Transcription Factors: Not All Created Equal. Plant Cell Physiology. 61(6):1025-1027.

Wang J, Singh SK, Geng S, Zhang S, Yuan L. (2020) Genome-wide analysis of glycerol-3-phosphate O-acyltransferase gene family and functional characterization of two cutin group GPATs in Brassica napus. Planta. 251(4):93.

Kong Q, Yang Y, Guo L, Yuan L, Ma W. (2020) Molecular Basis of Plant Oil Biosynthesis: Insights Gained From Studying the WRINKLED1 Transcription Factor. Frontiers in Plant Science. 11:24.

Paul P, Singh SK, Patra B, Liu X, Pattanaik S, Yuan L. (2020) Mutually Regulated AP2/ERF Gene Clusters Modulate Biosynthesis of Specialized Metabolites in Plants. Plant Physiology. 182(2):840-856.

Wang H, Wu Y, Zhang Y, Yang J, Fan W, Zhang H, Zhao S, Yuan L, Zhang P. (2019) CRISPR/Cas9-Based Mutagenesis of Starch Biosynthetic Genes in Sweet Potato (Ipomoea batatas) for the Improvement of Starch Quality. International Journal of Molecular Sciences. 20: 4702.

Kong Q, Yuan L, Ma W. (2019) WRINKLED1, a "Master Regulator" in Transcriptional Control of Plant Oil Biosynthesis. Plants (Basel). doi: 10.3390/plants8070238. 

Liu YL, Patra B., Pattanaik S, Wang Y, Yuan L. (2019) GATA and PIF transcription factors regulate light-induced biosynthesis of vindoline in Catharanthus. Plant Physiology. 180(3):1336-1350. 

Zhang Y, Deng G, Fan W, Yuan L, Wang H, Zhang P. (2019) NHX1 and eIF4A1-stacked transgenic sweet potato shows enhanced tolerance to drought stress. Plant Cell Rep. (in press) doi: 10.1007/s00299-019-02454-6.

Schluttenhofer C, Yuan L. (2019) Hemp hemp hooray for cannabis research. Science. 363(6428): 701-702 (Letter)

Jiang J, Xi H, Dai Z, Lecourieux F, Yuan L, Liu X, Patra B, Wei Y, Li S, Wang L (2018) VvWRKY8 negatively regulates VvSTS through direct interaction with VvMYB14 to balance resveratrol biosynthesis in grapevine. Journal of Experimental Botany. 70(2): 715-729

Sui X, Kumar Singh S, Patra B, Schluttenhofer C, Guo W, Pattanaik S, Yuan L. (2018) Cross-family Transcription Factor Interaction between MYC2 and GBFs Modulates Terpenoid indole Alkaloid Biosynthesis. Journal of Experimental Botany. 69(18): 4267-4281

Wang J, Wang X, Geng S, Singh SK, Wang Y, Pattanaik S, Yuan L. (2018) Genome-wide identification of hexokinase gene family in Brassica napus: structure, phylogenetic analysis, expression, and functional characterization. Planta. 248(1): 171-182

Yang X, Pan H, Yuan L, Zhou X (2018) Reference gene selection for RT-qPCR analysis in Harmonia axyridis, a global invasive lady beetle. Scientific Reports. 8(1): 2689

Liu Y, Song Y, Zeng S, Patra B, Yuan L, Wang Y (2018) Isolation and characterization of a salt stress-responsive betaine aldehyde dehydrogenase in Lycium ruthenicum Murr. Physiol Plant. 163(1): 73-87

Patra B, Pattanaik S, Schluttenhofer C, Yuan L. (2018) Jasmonate signaling regulates a network of bHLH factors to balance biosynthesis of monoterpenoid indole alkaloids in Catharanthus roseus. New Phytologist. 217(4):1566-1581

Feller A, Yuan L, Grotewold E (2017) The BIF Domain in Plant bHLH Proteins is an ACT-Like Domain. Plant Cell. 29(8):1800-1802. doi: 10.1105/tpc.17.00356

Schluttenhofer CM and Yuan L (2017) Challenges Towards Revitalizing Hemp - a Multifaceted Crop. Trends in Plant Science. 22(11):917-929.

Shen, EM, Singh, S, Ghosh JS, Patra B, Paul P, Yuan L, Pattanaik S (2017) The miRNAome of Catharanthus roseus: identification, expression analysis, and potential roles of microRNAs in regulation of terpenoid indole alkaloid biosynthesis.  Scientific Reports. 7:43027

Paul P, Singh S, Patra B, Sui X, Pattanaik S, Yuan L. (2017) A differentially regulated AP2/ERF transcription factor gene cluster acts downstream of a MAP kinase cascade to modulate terpenoid indole alkaloid biosynthesis in Catharanthus roseus. New Phytologist. 213(3):1107-1123

Wang J, Singh SK, Du C, Li C, Fan J, Pattanaik S, Yuan L (2016) Comparative transcriptomic analysis of two Brassica napus near-isogenic lines reveals a network of genes that influences seed oil accumulation. Frontiers in Plant Science. 7:1498

Huang W, Khaldun AB, Chen J, Zhang C, Lv H, Yuan L, Wang Y. (2016) A R2R3-MYB Transcription Factor Regulates the Flavonol Biosynthetic Pathway in a Traditional Chinese Medicinal Plant, Epimedium sagittatum. Frontiers in Plant Science. 7:1089.

Xu Z, Cheng K, Li X, Yang J, Xu S, Cao X, Hu X, Xie W, Yuan L, Ambrose M, Chen G, Mi H, Luo D (2016) Transcriptional and Post-transcriptional Modulation of SQU and KEW Activities in the Control of Dorsal-ventral Asymmetric Flower Development in Lotus japonicus. Molecular Plant. 9(5):722-736.

Wang JX, Nie J, Pattanaik S, Yuan L (2016) Efficient Agrobacterium-mediated transformationof Artemisia annua L. using young inflorescence. In Vitro Cellular & Developmental Biology - Plant. 52 (2): 204–211.

Wang H, Yang J, Zhang M, Fan W, Firon N, Pattanaik S, Yuan L, Zhang P (2015) Altered Phenylpropanoid Metabolism in the Maize Lc-Expressed Sweet Potato (Ipomoea batatas) Affects Storage Root Development. Scientific Reports. 6:18645.

Singh SK, Wu Y, Ghosh JS, Pattanaik S, Fisher C, Wang Y, Lawson D, Yuan L (2015) RNA-sequencing Reveals Global Transcriptomic Changes in Nicotiana tabacum Responding to Topping and Treatment of Axillary-shoot Control Chemicals.  Scientific Reports. 5:18148

Chen J, Xu Y, Wei G, Liao S, Zhang Y, Huang W, Yuan L, Wang Y (2015) Chemotypic and genetic diversity in Epimedium sagittatum from different geographical regions of China. Phytochemistry. 116:180-187.

Jia X, Shen J, Liu H, Li F, Ding N, Gao C, Pattanaik S, Patra B, Li R, Yuan L (2015) Small tandem target mimic-mediated blockage of microRNA858 induces anthocyanin accumulation in tomato. Planta 242(1):283-293.

Schluttenhofer CM, Yuan L (2015) Regulation of specialized metabolism by WRKY transcription factors.  Plant Physiology. 167 (2): 295-306.

Yuan L, Grotewold E (2015) Metabolic engineering to enhance the value of plants as green factories. Metabolic Engineering. 27:83-91

Schluttenhofer CM, Pattanaik S, Patra B, and Yuan L (2014) Analyses of Catharanthus roseus and Arabidopsis thaliana WRKY transcription factors reveal involvement in jasmonate signaling. BMC Genomics 15:502.

Pattanaik S, Patra B, Singh SK and Yuan L (2014) An overview of the gene regulatory network controlling trichome development in the model plant, Arabidopsis. Frontiers in Plant Cell Biology. 5:259.

Singh SK, Heng C, Braker JD, Chan V, Lee CC, Jordan, DB, Yuan L, Wagschal K (2014) Directed evolution of GH43 β-xylosidase XylBH43 thermal stability and L186 saturation mutagenesis. Journal of Industrial Microbiology & Biotechnology. 41(3):489-498

Yang Z, Patra B, Li R, Pattanaik S, Yuan L (2013) Characterization of the promoter of CrWRKY1 transcription factor. Gene. Planta. 238:1039–1049

Patra B, Pattanaik S, Yuan L (2013) Proteolytic degradation of the flavonoid regulators, TRANSPERENT TESTA8 and TRANSPERENT TESTA GLABRA1 in Arabidopsis is mediated by ubiquitin/26S proteasome system.  Plant Signal & Behavior. 8(10): e25901.

Xu YQ, Li ZZ, Yuan L, Zhang XJ, Lu DY, Huang HW, Ying Wang (2013) Variation of epimedins A, B, C and icariin in ten representative populations of Epimedium brevicornu Maxim., and implications for utilization.  Chemistry & Biodiversity. 10:711-721.

Huang W, Sun W, Lv H, Luo M, Zeng S, Pattanaik S, Yuan L, Wang Y (2013) A R2R3-MYB transcription factor from Epimedium sagittatum regulates the flavonoid biosynthetic pathway. PLoS One. 8(8):e70778.

Patra B, Schluttenhofer C, Wu Y, Pattanaik S, Yuan L (2013) Transcriptional regulation of secondary metabolism. Biochim Biophys Acta. 1829: 1236-1247.

Patra B, Pattanaik S, Yuan L (2013) Ubiquitin protein ligase 3 mediates the proteasomal degradation of GLABROUS3 and ENHANCER OF GLABROUS 3, regulators of trichome development and flavonoid biosynthesis in Arabidopsis.  The Plant Journal 74:435-437.

Kong Q, Pattanaik S, Feller A, Werkman JR, Chai C, Wang Y, Grotewold E, Yuan L (2012) A regulatory switch enforced by bHLH and ACT domain-mediated dimerization of the maize transcription factor R.  Proceeding of National Academy of Sciences, U.S. A. 109: E2091-2097

Suttipanta N, Pattanaik S, Kulshrestha M, Patra B, Singh SK, Yuan L (2011) The transcription factor CrWRKY1 positively regulates terpenoid indole alkaloid biosynthesis in Catharanthus roseus.  Plant Physiology 157: 2081-2093.

Jordan DB, Wagschal K, Fan ZM, Yuan L, Braker JD, Heng C (2011) Engineering lower inhibitor affinities in beta-D-xylosidase of Selenomonas ruminantium by site-directed mutagenesis of Trp145.  Journal of Industrial Microbiology and Biotechnology.  38: 1821-1835

Bai Y, Pattanaik S, Patra B, Werkman JR, Xie CH, Yuan L (2011) Flavonoid-related basic helix-loop-helix regulators, NtAn1a and NtAn1b, of tobacco have originated from two ancestors and are functionally active. Planta. 234: 363-375

Pattanaik S, Kong Q, Zaitlin D, Werkman JH, Xie CH, Patra B, Yuan L (2010) Isolation and functional characterization of a floral tissue-specific R2R3 MYB regulator from tobacco. Planta. 231: 1061-1076.

Fan ZM, Yuan L, Jordan DB, Wagschal K, Heng C, Braker JD (2010) Engineering lower inhibitor affinities in B-D-xylosidase.  Applied Microbiology and Biotechnology. 86: 1099-1113.

Fan ZM, Yuan L (2010) Production of multifunctional chimaeric enzymes in plants.  Plant Biotechnology Journal. 8: 308-315.

Fan ZM, Werkman JH, Yuan L (2009) Engineering a multifunctional hemicellulase.  Biotechnology Letters 31: 751-757

Fan ZM, Wagschal K, Chen W, Montross MD, Lee CC, Yuan L  (2009) Multimeric hemicellulases facilitate biomass conversion.  Applied and Environmental Microbiology. 75: 1754-1757

Fan ZM, Wagschal K, Lee CC, Kong Q, Shen KA, Maiti I, Yuan L (2009) The Construction and Characterization of Two Xylan-degrading Chimeric Enzymes. Biotechnology and Bioengineering. 102(3): 684-692

Fan ZM, Yuan L, Chatterjee R (2008) Increased Hydrogen Production by Genetic Engineering of Escherichia coli. PLoS One. 4(2): e4432

Pattanaik S, Xie CH, Yuan L (2008) The Interaction Domains of the Plant Myc-like bHLH Transcription Factors Can Regulate the Transactivation Strength. Planta. 227: 707-715.

Pattanaik S, Xie CH, Yuan L (2007) Creation of master transcription factors to regulate plant metabolic pathways. Acta Hort. 756: 109-118.

Zeng Q, Qiu F, Yuan L (2008) Production of Artemisinin by Genetically-modified microbes. Biotechnology Letters. 30: 581-592.

Suttipanta N, Pattanaik S, Gunjan S, Littleton J, Yuan L (2007) Promoter analysis of the Catharanthus roseus geranial 10-hydroxylase gene involved in terpenoid indole alkaloid biosynthesis. Biochim Biophys Acta. 1769: 139-148

Pattanaik S, Xie CH, Kong Q, Shen KA, Yuan L (2006). Directed evolution of plant basic helix­loop-helix transcription factors for the improvement of transactivational properties. Biochim Biophys Acta. 1759: 308-318

Chatterjee R, Yuan L (2006) Directed Metabolic Pathway Evolution. Trends in Biotechnology. 24(1): 28-38.

Yuan L, Kurek I, English J, Keenan R (2005) Laboratory-Directed Protein Evolution. Microbiology and Molecular Biology Reviews. 69(3): 373-392